Patent · US Active

Methods and compositions for inhibiting or reducing hair loss, acne, rosacea, prostate cancer, and BPH

US9254293B2 · kind B2 · utility

1Cited by
0References
2Claims
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Assignee

Inventors

Key dates

Filing dateJun 15, 2007
Grant dateFeb 9, 2016
Priority date—
Expiry dateMar 11, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2830/008
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides methods of treating androgenetic alopecia (AGA), acne, rosacea, prostate cancer, and benign prostatic hypertrophy (BPH), comprising the step of contacting a subject with a compound or composition capable of decreasing prostaglandin D2 (PGD2) level or activity, a downstream signaling or receptor pathway thereof, or prostaglandin D2 synthase level or activity; methods of stimulating hair growth, comprising the step of contacting a subject with a compound or composition capable of increasing or decreasing the activity or level of a target gene of the present invention, or with a protein product of the target gene or an analog or mimetic thereof; and methods of testing for AGA and evaluating therapeutic methods thereof, comprising measuring PGD2 levels.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.