Patent · US Active

Multimeric IL-15 soluble fusion molecules and methods of treating neoplasia and HIV using same

US9255141B2 · kind B2 · utility

37Cited by

6References

16Claims

0Family size

Inventors

Hing C. Wong · San Ramon, US
Peter Rhode · Culver City, US
Bai Liu · Culver City, US
Xiaoyun Zhu · Miami, US
Kai-Ping Han · Weston, US

Key dates

Filing date	Feb 15, 2013
Grant date	Feb 9, 2016
Priority date	—
Expiry date	Feb 15, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.