Patent · US Active

Method of producing erythrocytes without feeder cells

US9255248B2 · kind B2 · utility

5Cited by
116References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 11, 2013
Grant dateFeb 9, 2016
Priority date
Expiry dateOct 11, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2506/03
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Provided herein are methods of producing erythrocytes from hematopoietic cells, particularly hematopoietic cells from placental perfusate in combination with hematopoietic cells from umbilical cord blood, wherein the method results in accelerated expansion and differentiation of the hematopoietic cells to more efficiently produce administrable erythrocytes. Further provided herein is a bioreactor in which hematopoietic cell expansion and differentiation takes place.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.