Vaccine comprising protein NMB0964 from Neisseria meningitidis
US9259461B2 · kind B2 · utility
2Cited by
0References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 6, 2009 |
| Grant date | Feb 16, 2016 |
| Priority date | — |
| Expiry date | May 6, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/575
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to immunogenic compositions comprising neisserial blebs with upregulated levels of the NMB0964 antigens such that bacterial antibodies are generated against said antigen. Methods are also provided to upregulate expression through removal of the zinc repression mechanism of the cell or promoter or through removal of zinc from the culture medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.