Peptide sequence design and use thereof for peptide-mediated siRNA delivery
US9259483B2 · kind B2 · utility
2Cited by
2References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 23, 2012 |
| Grant date | Feb 16, 2016 |
| Priority date | — |
| Expiry date | Nov 23, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides, in one aspect, peptides and a complex comprising one of the peptides and a cargo molecule, wherein the peptide and the cargo molecule are coupled by non-covalently. The peptides of the invention were found to facilitate the delivery of siRNA molecules into cells and to function in siRNA mediated silencing of cellular targets.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.