Patent · US Active

Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile

US9260411B2 · kind B2 · utility

0Cited by

3References

8Claims

0Family size

Assignee

Abb Vie Inc. · US

Inventors

Todd McDermott · Oak Park, US
Seble H. Wagaw · Lake Bluff, US
Kenneth M. Engstrom · Mundelein, US
Jorge Gandarilla · North Riverside, US
Albert W. Kruger · Pleasant Prairie, US
Michael J. Rozema · Kenosha, US
Michael G. Fickes · Evanston, US
Steven J. Wittenberger · Mundelein, US
Lakshmi Bhagavatula · Vernon Hills, US
Thomas B. Borchardt · Kenosha, US

Key dates

Filing date	Jul 19, 2007
Grant date	Feb 16, 2016
Priority date	—
Expiry date	Dec 3, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F7/0803
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.