Therapeutic methods and compositions involving allosteric kinase inhibition
US9260417B2 · kind B2 · utility
0Cited by
44References
19Claims
0Family size
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Key dates
| Filing date | Feb 7, 2011 |
| Grant date | Feb 16, 2016 |
| Priority date | — |
| Expiry date | Nov 9, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/46
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to methods and compositions for suppressing lymphangiogenesis, angiogenesis and/or tumor growth. The methods comprise contacting the tumor with a compound that (i) stabilizes a protein kinase in the inactive state and (ii) is not an ATP competitive inhibitor of the protein kinase in the active state.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.