Capture and elution of bio-analytes via beads that are used to disrupt specimens
US9260475B2 · kind B2 · utility
11Cited by
23References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 24, 2010 |
| Grant date | Feb 16, 2016 |
| Priority date | — |
| Expiry date | Apr 18, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/00524
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Lysing may include agitating a specimen in a chamber along with a medium that includes a particulate lysing material that has an affinity for a biological material. Lysing material may include beads or other material which may be coated that facilitates binding. The medium may include a fluid with a high salt or low pH level. The biological material may be eluted by lowering a concentration of salt or increasing a pH level. Lysing materials with two or more different affinities may be employed. Heating may be used. Lysing may be performed in a flow through apparatus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.