Potent and efficient cytotoxic peptides and antibody-drug conjugates thereof and their synthesis
US9260478B2 · kind B2 · utility
0Cited by
1References
3Claims
0Family size
Inventors
Key dates
| Filing date | Oct 16, 2014 |
| Grant date | Feb 16, 2016 |
| Priority date | — |
| Expiry date | Oct 16, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a family of novel cytotoxic pentapeptides, which show potent antitumor activities against several cancer lines. The antibody-drug conjugates prepared from those pentapeptides can efficiently kill cancer cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.