Patent · US Active

SMB process

US9260677B2 · kind B2 · utility

1Cited by
80References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 6, 2012
Grant dateFeb 16, 2016
Priority date
Expiry dateJul 6, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC11C1/007
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which process comprises the steps of: (i) purifying the feed mixture in a first separation step in a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain an intermediate product; and (ii) purifying the intermediate product obtained in (i) in a second separation step using a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain the PUFA product; wherein (a) the first and second separation steps are carried out sequentially on the same chromatography apparatus, the intermediate product being recovered between the first and second separation steps and the process conditions in the chromatography apparatus being adjusted between the first and second separation steps such that the PUFA product is separated from different components of the feed mixture in each separation step; or (b) the first and second separation …

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