Connexin mutation detection for lymphatic variation and disease
US9260754B2 · kind B2 · utility
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Key dates
| Filing date | May 12, 2011 |
| Grant date | Feb 16, 2016 |
| Priority date | — |
| Expiry date | Jul 30, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods are provided for identifying risk of developing lymphedema, including primary and secondary edema. The methods comprise identifying the presence in a biological sample of a polymorphism in one or more of GJA4, GJA5 and GJC2, resulting in a functional mutation of one or more of connixin 37 (Cx37), Cx40 or Cx47.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.