Patent · US Active

Derivatives of protoberberine biological alkaloids and use of same inhibiting ulcerative colitis

US9266897B2 · kind B2 · utility

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7Claims

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Assignee

INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES · CN

Inventors

Hailin Qin · Beijing, CN
Wenjie Wang · Beijing, CN
Zhihui Zhang · Katy, US
Lianqiu Wu · Beijing, CN
Anjun Deng · Beijing, CN
Jinqian Yu · Jinan, CN
Zhihong Li · San Jose, US

Key dates

Filing date	Oct 24, 2012
Grant date	Feb 23, 2016
Priority date	—
Expiry date	Oct 24, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/147
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Disclosed are derivatives of protoberberine biological alkaloids or physiologically acceptable salts thereof produced by means of a derivative reaction of a source material of biological alkaline quaternary ammonium salts of protoberberine alkaloids, a preparation method for same and pharmaceutical uses thereof. The derivatives of protoberberine biological alkaloids or the physiologically acceptable salts thereof show activity inhibiting ulcerative colitis and can be used in the preparation of drugs for same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.