Methods of modulating MicroRNAs in the treatment of pulmonary arterial hypertension
US9267134B2 · kind B2 · utility
1Cited by
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20Claims
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Key dates
| Filing date | May 9, 2012 |
| Grant date | Feb 23, 2016 |
| Priority date | — |
| Expiry date | May 9, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3231
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method of treating or preventing pulmonary arterial hypertension in a subject in need thereof by administering to the subject an inhibitor of miR-145 expression or activity. Pharmaceutical compositions and kits comprising miR-145 inhibitors for treating pulmonary arterial hypertension are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.