Method for detection of specific immunoglobulin class G antibodies

US9267953B2 · kind B2 · utility

Assignee

• Roche Diagnostics Operations, Inc. · US

Inventors

• Barbara Upmeier · Iffeldorf, DE
• Ralf Bollhagen · Penzberg, DE
• Martina Bronold · Wolfratshausen, DE
• Frederic Donie · Penzberg, DE
• Christine Markert-Hahn · Penzberg, DE

Key dates

• Filing date: Jun 17, 2010
• Grant date: Feb 23, 2016
• Expiry date: Mar 14, 2031

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/5438
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods for determining an analyte in a sample by immunoassay in a one-step format without performing washing steps are described. The method includes a first analyte-specific receptor that contains at least two binding sites for the analyte, and a second analyte-specific receptor that selectively binds to an aggregate arrangement of at least two analyte molecules bound to the first receptor.