Controlled dispensing of samples onto substrates
US9269138B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 15, 2013 |
| Grant date | Feb 23, 2016 |
| Priority date | — |
| Expiry date | Nov 28, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/10056
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for dispensing a fluid sample on a substrate include obtaining an image of a sample applicator in proximity to the substrate, where the image includes a first image of the sample applicator and a second image of the sample applicator, determining a height of the sample applicator relative to a surface plane of the substrate based on a distance between common portions of the first and second images, and dispensing the fluid sample onto the substrate using the sample applicator, where the dispensing includes: translating the sample applicator, translating the substrate, or translating both the sample applicator and the substrate to effect a relative translation between the sample applicator and the substrate; and maintaining the sample applicator within 2 microns of a target height relative to the surface plane of the substrate during the translating.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.