Intra-operative molecular imaging
US9271653B2 · kind B2 · utility
5Cited by
3References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 30, 2013 |
| Grant date | Mar 1, 2016 |
| Priority date | — |
| Expiry date | Sep 30, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16H50/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A system for detecting tumor margins includes a topical protease-specific, fluorescence imaging probe that is activatable by enzymatic activation to produce a visually differentiated signal upon topical application to a targeted cancer cell that secretes an enzyme that activates the protease-specific, fluorescence imaging probe, an applicator for topically administering the imaging probe to the cancer cell; and an imaging device to detect activation of the imaging probe administered to the cancer cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.