Patent · US Active

Methods to enhance RNAi oligonucleotide delivery to respiratory epithelial cells

US9272016B2 · kind B2 · utility

0Cited by
7References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 14, 2013
Grant dateMar 1, 2016
Priority date
Expiry dateJul 10, 2033

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/713
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a sensitizing agent followed by contacting the cell with a therapeutic RNAi agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.