Method and apparatus for maintaining microcarrier beads in suspension
US9272251B2 · kind B2 · utility
3Cited by
11References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 23, 2010 |
| Grant date | Mar 1, 2016 |
| Priority date | — |
| Expiry date | Mar 4, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M47/12
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to an impeller for use in a bioreactor for growing adherent mammalian cells and/or a cell separator for adherent mammalian cells. The impeller of the invention is designed to efficiently and rapidly lift a bed of settled cells and microcarrier beads at low rotational speeds. Cell growth and concomitant yield is therefore improved by maintaining the culture in an environment of low shear force.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.