Patent · US Active

Spirocyclic morphinans and their use

US9273048B2 · kind B2 · utility

10Cited by

30References

18Claims

0Family size

Assignee

PURDUE PHARMA L.P. · US

Inventors

R. Richard Goehring · Pipersville, US
Laykea Tafesse · Robinsville, US
Mark A. Youngman · Warminster, US

Key dates

Filing date	Jan 28, 2015
Grant date	Mar 1, 2016
Priority date	—
Expiry date	Jan 28, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The application is directed to compounds of Formula I′-Aand especially to compounds of Formula I-Aand pharmaceutically acceptable salts and solvates thereof, wherein R1a-R5a, Y, Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I′-A, and especially compounds of Formula I-A, to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.