Patent · US Active

α4β7 peptide dimer antagonists

US9273093B2 · kind B2 · utility

29Cited by

9References

8Claims

0Family size

Assignee

Protagonist Therapeutics, Inc. · US

Inventors

Ashok Bhandari · Pleasanton, US
Dinesh V. Patel · Fremont, US
Larry C. Mattheakis · Cupertino, US

Key dates

Filing date	Oct 10, 2013
Grant date	Mar 1, 2016
Priority date	—
Expiry date	Oct 10, 2033

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to disulfide-rich dimer molecules which inhibit binding of α4β7 to the mucosal addressin cell adhesion molecule (MAdCAM) in vivo, and show high selectivity against α4β1 binding.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.