Antibody for detecting DNA damage in cells utilizing cell membrane surface antigen Ly6D
US9273140B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | May 10, 2013 |
| Grant date | Mar 1, 2016 |
| Priority date | — |
| Expiry date | May 10, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/622
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
To provide a method for detecting cellular DNA damage by specifically recognizing molecules responsive to DNA strand breaks. A method for detecting DNA damage in cells, which comprises administering in vivo, to cells, an antibody against a cell membrane surface antigen that is expressed in cells undergoing DNA strand breaks to a greater extent than in cells not undergoing DNA strand breaks in an environment that causes DNA damage, and analyzing the expression status of the cell membrane surface antigen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.