System and method for patient specific planning and guidance of ablative procedures for cardiac arrhythmias

US9277970B2 · kind B2 · utility

Assignee

• Siemens Aktiengesellschaft · DE

Inventors

• Tommaso Mansi · Plainsboro, US
• Olivier Ecabert · Aachen, DE
• Saikiran Rapaka · Ewing, US
• Bogdan Georgescu · Plainsboro, US
• Ali Kamen · Skillman, US
• Dorin Comaniciu · Princeton Junction, US

Key dates

• Filing date: Jul 19, 2013
• Grant date: Mar 8, 2016
• Expiry date: Jul 6, 2034

Classification

• Technology area (CPC G): Physics
• CPC primary: G16H50/50
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method and system for patient-specific planning and guidance of an ablation procedure for cardiac arrhythmia is disclosed. A patient-specific anatomical heart model is generated based on pre-operative cardiac image data. The patient-specific anatomical heart model is registered to a coordinate system of intra-operative images acquired during the ablation procedure. One or more ablation site guidance maps are generated based on the registered patient-specific anatomical heart model and intra-operative patient-specific measurements acquired during the ablation procedure. The ablation site guidance maps may include myocardium diffusion and action potential duration maps. The ablation site guidance maps are generated using a computational model of cardiac electrophysiology which is personalized by fitting parameters of the cardiac electrophysiology model using the intra-operative patient-specific measurements. The ablation site guidance maps are displayed by a display device during the ablation procedure.