Particle composition and pharmaceutical composition using particle composition

US9278075B2 · kind B2 · utility

Assignees

• NANOCARRIER CO., LTD. · JP
• THE UNIVERSITY OF TOKYO · JP

Inventors

• Kazunori Kataoka · Bunkyo, JP
• Ronald James Christie · Gaithersburg, US
• Nobuhiro Nishiyama · Tokyo, JP
• Kanjiro Miyata · Tokyo, JP
• Shigeto Fukushima · Narashino, JP
• Yu Matsumoto · Tokyo, JP
• Takahiro Nomoto · Tokyo, JP
• Yasuki Kato · Kashiwa, JP

Key dates

• Filing date: Jan 16, 2012
• Grant date: Mar 8, 2016
• Expiry date: Aug 7, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A composition of matter for use in encapsulating a drug is expressed by formula (1) or formula (2):wherein R1 and R2 are each independently a hydrogen atom or a substituted or unsubstituted, linear or branched alkyl group having 1 to 12 carbon atoms; A is a hydrophilic polymer chain; L1 and L3 are each a linking group; B is a cation-containing group; R3 is a side chain of an amino acid; z is an integer of 5 to 500; x is an integer of 40% or more of z; y is 0 or a positive integer; z-x-y is 0 or a positive integer; p is an integer of 1 to 10; and q is an integer of 1 to 10.