Crystal form of prostaglandin analogue, and preparation method and use thereof

US9278902B2 · kind B2 · utility

Assignee

• SHANGHAI TECHWELL BIOPHARMACEUTICAL CO., LTD. · CN

Inventors

• Zhijun Tang · Shanghai, CN
• Yubin Liu · Shanghai, CN
• Bingming He · Shanghai, CN
• Jun Yang · Oak Ridge, US
• Xiaoming Ji · Sunnyvale, US

Key dates

• Filing date: Jan 10, 2013
• Grant date: Mar 8, 2016
• Expiry date: Jan 10, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Provided are a crystal form B of a compound having the structure as represented by formula I, and preparation method and use thereof. The X-ray powder diffraction (XRPD) chart of the crystal form B has characteristic peaks at the following diffraction angles: 2.9±0.2°, 6.5±0.2°, 12.6±0.2°, 13.1±0.2° and 20.6±0.2°.