C13-hydroxy derivatives of oleanolic acid and methods of use thereof
US9278912B2 · kind B2 · utility
29Cited by
40References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 10, 2013 |
| Grant date | Mar 8, 2016 |
| Priority date | — |
| Expiry date | Sep 10, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J63/008
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein are novel C13-hydroxy derivatives of oleanolic acid, including those of the formula:wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds, for example, as antioxidant inflammation modulators, and compositions thereof are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.