Imidazopyridine compounds
US9278968B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 28, 2013 |
| Grant date | Mar 8, 2016 |
| Priority date | — |
| Expiry date | Nov 28, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
[Problem]A pharmaceutical composition for treating or preventing various cardiovascular diseases, which have sGC activities based on improvement of cGMP signals, is provided.[Means for Solution]It was found that imidazo[1,2-a]pyridine compounds having a carbamoyl group at the 3-position and a particular cyclic group at the 8-position via a methyleneoxy group, or a salt thereof have sGC activation, and are useful as active ingredients of pharmaceutical compositions for treating or preventing various sGC-related cardiovascular diseases, in particular, peripheral arterial diseases, intermittent claudication, critical limb ischemia, hypertension, and pulmonary hypertension, thereby completing the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.