Halofuginone analogs for inhibition of tRNA synthetases and uses thereof
US9284297B2 · kind B2 · utility
26Cited by
28References
29Claims
0Family size
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Key dates
| Filing date | Aug 11, 2009 |
| Grant date | Mar 15, 2016 |
| Priority date | — |
| Expiry date | Apr 16, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65583
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel analogs and derivatives of halofuginone. The invention also provides pharmaceutical and cosmetic compositions thereof and methods for using halofuginone analogs in treating chronic inflammatory diseases, autoimmune diseases, dry eye syndrome, fibrosis, scar formation, angiogenesis, viral infections, ischemic damage, transplant and implant rejection, neurodegenerative diseases, and cosmetic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.