Heterocyclyl aminoimidazopyridazines

US9284319B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Knut Eis · Berlin, DE
• Florian Pühler · Berlin, DE
• Ludwig Zorn · Berlin, DE
• Arne Scholz · Berlin, DE
• Philip Lienau · Berlin, DE
• Mark Jean Gnoth · Mettmann, DE
• Ulf Bömer · Glienicke, DE
• Judith Günther · Berlin, DE
• Jörg Fanghänel · Berlin, DE
• Daniel Korr · Berlin, DE

Key dates

• Filing date: Jun 21, 2012
• Grant date: Mar 15, 2016
• Expiry date: Jun 21, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to heterocyclyl aminoimidazopyridazine compounds of general formula (I): in which A, R1, R2, R3 and R4 are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.