Designed repeat proteins binding to serum albumin
US9284361B2 · kind B2 · utility
8Cited by
10References
31Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 25, 2011 |
| Grant date | Mar 15, 2016 |
| Priority date | — |
| Expiry date | Nov 25, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New designed repeat proteins with binding specificity for serum albumin are described, as well as nucleic acids encoding such serum albumin binding proteins, pharmaceutical compositions comprising such proteins, the use of such proteins to modify the pharmacokinetics of therapeutic relevant polypeptides and the use of such proteins in the treatment of diseases. The repeat proteins of the invention have a substantially increased half-life in plasma compared to proteins not binding serum albumin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.