Isolated nucleic acid molecule encoding a fusion protein comprising an activin receptor
US9284364B2 · kind B2 · utility
10Cited by
49References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 20, 2013 |
| Grant date | Mar 15, 2016 |
| Priority date | — |
| Expiry date | Nov 20, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel activin IIB5 receptor polypeptides capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the receptor polypeptides. Compositions and methods for treating muscle-wasting, metabolic and other disorders are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.