Valve prosthesis

US9289291B2 · kind B2 · utility

Assignee

• The Trustees of the University of Pennsylvania · US

Inventors

• Joseph H. Gorman, III · North Wales, US
• Robert C. Gorman · North Wales, US
• Matthew J. Gillespie · Via Enrico Fermi, US

Key dates

• Filing date: Nov 5, 2010
• Grant date: Mar 22, 2016
• Expiry date: Apr 2, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61F2250/0069
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The present disclosure relates to valve replacement devices that are foldable for catheter-based deployment to the site of implantation, as well as systems for the delivery of valve prostheses, including prostheses having the special characteristics of the disclosed valve replacement devices. The devices include highly effective adhering mechanisms for secure and enduring precision implantation. The adhering mechanisms may employ a unique sealing mechanism that includes a cuff that expands slowly whereby the device is not secured in place until the completion of the implantation procedure. The implanted device, optionally together with the cuff, prevents perivalvular leaks and incorporate an appropriate leaflet system for reliable functioning in situ.