Vaccine engineering
US9289488B2 · kind B2 · utility
3Cited by
10References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 12, 2011 |
| Grant date | Mar 22, 2016 |
| Priority date | — |
| Expiry date | Aug 31, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2440/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The method and constructs disclosed and claimed herein allow to control peptide conformation by modulation of the peptide lipidation pattern, spacer and liposome composition, or via co-administration with small molecules. Accordingly, this technology can be applied to the rational design of liposomal vaccines and for the generation of safer and more efficacious therapies for a range of human disease, in particular those based on misfolded proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.