Hypervalent radioactive astatine or iodine compounds, and preparation methods thereof
US9290421B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Feb 2, 2011 |
| Grant date | Mar 22, 2016 |
| Priority date | — |
| Expiry date | Nov 28, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/2208
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a compound having formula (I): wherein: —X is in particular 125I Or 211At; —R1 and R′1 are independently from each other chosen preferably from the group consisting of electron-withdrawing groups and alkyl groups; —R2 is chosen from the group consisting of: H, alkyl groups, functional groups being able to bind a vector, and functional groups having targeting properties which make the compound of the invention a vector itself; —Z is a heteroatom, R5, R8 and R9 are preferably H; —Y is preferably an electron withdrawing group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.