Process for the preparation of derivatives of 1-(2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid

US9290428B2 · kind B2 · utility

Assignee

• Chiesi Farmaceutici S.p.A. · IT

Inventors

• Massimo Verzini · San Bonifacio, IT
• Livius Cotarca · Palmanova, IT
• Alberto Guidi · Lonigo, IT
• Alfonso Melloni · Bresso, IT
• Paolo Maragni · Mantova, IT

Key dates

• Filing date: Jun 23, 2014
• Grant date: Mar 22, 2016
• Expiry date: Jun 23, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein R is as defined above and G is —CN or —COOR2 wherein R2 is a C1-C4 straight or branched alkyl chain.