Thieno-pyrimidines, useful as potassium channel inhibitors
US9290511B2 · kind B2 · utility
14Cited by
4References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 15, 2012 |
| Grant date | Mar 22, 2016 |
| Priority date | — |
| Expiry date | Nov 15, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/048
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds of formula (I): (Formula (I); wherein A, R1, R2, R3I, V, X, and Z are defined herein, which are potassium channel inhibitors. The invention further provides pharmaceutical compositions comprising the compounds of formula (I) and their use in therapy, in particular in treatment of diseases or conditions that are mediated by Kir3.1 and/or Kir3.4 or any heteromultimers thereof, or that require inhibition of Kir3.1 and/or Kir3.4 or any heteromultimers thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.