Patent · US Active

Peptides that modulate complex SASPase-FLG2

US9290553B2 · kind B2 · utility

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Inventors

Key dates

Filing dateDec 5, 2011
Grant dateMar 22, 2016
Priority date
Expiry dateDec 5, 2031

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2500/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An isolated peptide from skin aspartic protease (SASPase) or filaggrin-2 (FLG2), a fragment or homologue thereof, which can modify the three-dimensional shape of a complex formed by interaction between a first amino acid sequence from filaggrin-2 and a second amino acid sequence from SASPase, is described. The isolated peptide is useful as a target for screening for cosmetic or therapeutic active agents with regard to the skin and/or its appendages.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.