Composition containing 2-acyl-lysophosphatidylserine and method for producing the same
US9290781B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 26, 2011 |
| Grant date | Mar 22, 2016 |
| Priority date | — |
| Expiry date | Sep 26, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/6481
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for producing a composition containing 2-acyl-lysophosphatidylserine, including (a) a step of obtaining a composition containing phosphatidylserine by allowing phospholipase D to act on a raw material containing phosphatidylcholine in the presence of serine and (b) a step of obtaining a composition containing 2-acyl-lysophosphatidylserine by allowing phospholipase A1 to act on the composition containing phosphatidylserine in the presence of one or more additives selected from the group consisting of the following (I), (II), and (III), in which (I) one or more salts selected from the group consisting of sulfate salts, phosphate salts, nitrate salts, citrate salts, and tartarate salts of monovalent cations, (II) a gum, and (III) an emulsifier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.