Methods and compositions for separating rare cells from fluid samples
US9290812B2 · kind B2 · utility
2Cited by
111References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 28, 2014 |
| Grant date | Mar 22, 2016 |
| Priority date | — |
| Expiry date | May 28, 2034 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/25375
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention includes methods of enriching rare cells, such as cancer cells, from biological samples, such as blood samples. The methods include performing at least one debulking step on a blood sample and selectively removing at least one type undesirable component from the blood sample to obtain a blood sample that is enriched in a rare cell of interest. In some embodiments magnetic beads coupled to specific binding members are used to selectively removed components.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.