Pathogen detection biosensor

US9291549B2 · kind B2 · utility

Assignee

• Massachusetts Institute of Technology · US

Inventors

• Eric Schwoebel · Woburn, US
• James D. Harper · Hazel Green, US
• Martha S. Petrovick · Barre, US
• Frances E. Nargi · Littleton, US
• Mark A. Hollis · Concord, US
• Bernadette Johnson · Hollis, US
• Joseph Lacirignola · Beverly, US
• Richard H. Mathews · Chelmsford, US
• Kristine E. Hogan · Danvers, US
• Trina Rae Vian · Westford, US
• Allan Heff · Watertown, US
• Mark Hennessy · Cambridge, US
• Songeeta Palchaudhuri · Somerville, US
• Todd H. Rider · Littleton, US

Key dates

• Filing date: Apr 24, 2012
• Grant date: Mar 22, 2016
• Expiry date: Jan 15, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/582
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention described herein provides methods for the detection of target particles, such as pathogens, soluble antigens, nucleic acids, toxins, chemicals, plant pathogens, blood borne pathogens, bacteria, viruses and the like. Also described is an emittor cell comprising a receptor, wherein the receptor can be an antibody or an Fc receptor, and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more receptors on the emittor cell. Also provided are optoelectronic sensor devices for detecting a target particle in a sample, including in a plurality of samples.