Diagnosis and treatment of chronic obstructive pulmonary disease (COPD)
US9291626B2 · kind B2 · utility
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37Claims
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Key dates
| Filing date | May 11, 2012 |
| Grant date | Mar 22, 2016 |
| Priority date | — |
| Expiry date | May 11, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/56
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided is a method for diagnosing and/or staging COPD based on detection of one or more histone proteins. In some embodiments, the histone protein is an H3.3 protein comprising a post-translational modification. In some embodiments, the histone protein is H2B, H3, H3.3 or H4. Kits for practicing the methods of diagnosis and/or staging are provided as well. Further provided is a method for treating COPD.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.