Method for making rhenium-186/188 labeled human serum albumin microspheres and kit for making the same and method for using the kit
US9295740B2 · kind B2 · utility
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Key dates
| Filing date | Jun 29, 2012 |
| Grant date | Mar 29, 2016 |
| Priority date | — |
| Expiry date | May 26, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for preparing 186/188Re-labeled human serum albumin (HSA) microspheres by 186/188Re(I)-tricarbonyl ion. This radioactive particle can be subjected to radioembolization for liver tumor. In this method, 186/188Re(I)-tricarbonyl ion (186/188Re(OH2)3(CO)3)+) are employed as a precursor for directly labeling HSA microspheres with 186/188Re at appropriate temperature.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.