Methods for inducing immune tolerance to organ transplants
US9295756B2 · kind B2 · utility
0Cited by
8References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 31, 2013 |
| Grant date | Mar 29, 2016 |
| Priority date | — |
| Expiry date | Jan 31, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01N1/126
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to methods of treating an organ or a tissue prior to transplantation thereof into a recipient, comprising ablating the cells composing the blood vessels of said organ or tissue, preferably the cells lining the lumen surface of the blood vessels, thereby obtaining a treated viable organ or tissue having reduced immunogenicity. The invention is also directed to treated viable organs or tissues having reduced immunogenicity and uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.