Prosthesis having varied concentration of beneficial agent

US9296011B2 · kind B2 · utility

Assignee

• Abbott Laboratories · US

Inventors

• Donald Verlee · Libertyville, US
• Peter Tarcha · Lake Villa, US
• Keith Cromack · Lake Bluff, US
• Sandra E. Burke · Libertyville, US
• Anton G. Clifford · Mountain View, US
• John L. Toner · Libertyville, US
• Charles Fisher · Loveland, US

Key dates

• Filing date: Nov 7, 2003
• Grant date: Mar 29, 2016
• Expiry date: Mar 21, 2026

Classification

• Technology area (CPC G): Physics
• CPC primary: G11B7/00
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

An interventional device for delivery of beneficial agent to a lumen and methods of loading and manufacture of the same, which include a prosthesis loaded with beneficial agent to provide a controlled dosage concentration of beneficial agent to the lumen. The beneficial agent is loaded onto the prosthesis by a fluid-dispenser having a dispensing element capable of dispensing the beneficial agent in discrete droplets, each droplet having a controlled trajectory. The interventional device has a controlled local areal density of beneficial agent for systemic delivery or delivery to the luminal wall. The local areal density of beneficial agent may be varied along the prosthesis. The interventional device includes overlapping or bifurcated stents having a controlled areal density of beneficial agent.