Preparation of 3,5-dioxo hexanoate ester in two steps
US9296718B2 · kind B2 · utility
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3References
20Claims
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Key dates
| Filing date | Aug 28, 2014 |
| Grant date | Mar 29, 2016 |
| Priority date | — |
| Expiry date | Aug 28, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention discloses a method for the preparation of tert-butyl 6-chloro-3,5-dioxohexanoate from Meldrum's acid derivative and its use for the preparation of tert-butyl (4R,6S)-(6-hydroxymethyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate (BHA), Rosuvastatin and Atorvastatin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.