Diacylglycerol acyltransferase 2 inhibitors

US9296745B2 · kind B2 · utility

Assignee

• PFIZER INC. · US

Inventors

• Kay Ahn · Lexington, US
• Markus Boehm · Mansfield, US
• Shawn Cabral · Groton, US
• Philip A. Carpino · Groton, US
• Kentaro Futatsugi · Sharon, US
• David Hepworth · Concord, US
• Daniel Wei-Shung Kung · Salem, US
• Suvi Tuula Marjukka Orr · San Diego, US
• Jian Wang · Newton, US

Key dates

• Filing date: Mar 26, 2013
• Grant date: Mar 29, 2016
• Expiry date: Mar 26, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Derivatives of purine, 3H-imidazo[4,5-b]pyrimidine and 1H-imidazo[4,5-d]pyrazine of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.