Patent · US Active

Process for isolation and purification of a target protein free of prion protein (PrPSC)

US9296799B2 · kind B2 · utility

0Cited by

0References

4Claims

0Family size

Assignee

OCTAPHARMA AG · CH

Inventors

Gustav Gilljam · Älta, SE
Mats Jernberg · Stockholm, SE
Stefan Winge · Kramfors, SE
Andrea Neisser-Svae · Spittal an der Drau, AT

Key dates

Filing date	Aug 25, 2008
Grant date	Mar 29, 2016
Priority date	—
Expiry date	Apr 28, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/30
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

A process for isolation and purification of a target protein by chromatography wherein the chromatography removes or depletes prions (PrPSC), comprising the steps of contacting a potentially PrPSC contaminated sample comprising a target protein with a multimodal chromatographic material; setting buffer conditions so that the target protein is bound to the multimodal chromatographic material and whereas PrPSC is not binding to the multimodal chromatographic material; followed by elution of the target protein. a process for isolation and purification of a target protein free of prion protein (prpSC).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.