Method of making monomethyl fumarate
US9302977B2 · kind B2 · utility
11Cited by
42References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 6, 2014 |
| Grant date | Apr 5, 2016 |
| Priority date | — |
| Expiry date | Jun 23, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/185
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Methods of making monomethyl fumarate, which can then also be used in methods of making prodrugs of monomethyl fumarate, are disclosed. Monomethyl fumarate and prodrugs of monomethyl fumarate are useful for treating neurodegenerative, inflammatory, and autoimmune diseases including multiple sclerosis, psoriasis, irritable bowel disorder, ulcerative colitis, arthritis, chronic obstructive pulmonary disease, asthma, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.