Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof
US9302986B2 · kind B2 · utility
13Cited by
5References
11Claims
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Key dates
| Filing date | Apr 5, 2013 |
| Grant date | Apr 5, 2016 |
| Priority date | — |
| Expiry date | Apr 5, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/63
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The preparation and pharmaceutical use of substituted 3-haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula I:is described. Methods of using compounds of Formula I, or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases, ocular diseases, fibrotic diseases, diabetes-induced diseases and cancer, are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.