Fluoromethyl-substituted pyrrole carboxamides

US9302988B2 · kind B2 · utility

Assignee

• GRÜNENTHAL GMBH · DE

Inventors

• Stefan Schunk · Aachen, DE
• Melanie Reich · Aachen, DE
• Henning Steinhagen · Pocking, DE
• Nils Damann · Bad Mergentheim, DE
• Michael Haurand · Aachen, DE
• Achim Kless · Aachen, DE
• Philip Alan Skone · Stevenage, GB
• Richard John Hamlyn · St Ives, GB
• Robert KIRBY · Cambridge, GB
• Marc Rogers · St Ives, GB
• Kathy Sutton · Maidstone, GB

Key dates

• Filing date: Aug 29, 2013
• Grant date: Apr 5, 2016
• Expiry date: Aug 29, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.