Method and system for cell and tissue cultivation
US9303257B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 1, 2010 |
| Grant date | Apr 5, 2016 |
| Priority date | — |
| Expiry date | Aug 1, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N11/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A cell cultivating platform includes a substrate having a surface, at least one actuator moveable relative to the substrate, and a deformable material layer positioned above at least a portion of the supporting surface and the at least one actuator. The deformable material layer positioned opposite the substrate surface includes a biocompatible supportive surface suitable for supporting cultivated cells. The supportive surface deforms or otherwise deflects in response to activation of the at least one actuator, effectively releasing at least a portion of the cultured cells from the supportive surface. Suitable actuators include piezoelectric actuators that can be selectively energized according to one or more patterns to facilitate separation of cells from the supportive surface. Such activation cycles can be repeated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.